PeptideDB

[D-Trp7,9,10]-Substance P

CAS: 89430-38-6 F: C79H105N21O13S W: 1588.88

-Substance P is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductance t
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Bioactivity [D-Trp7,9,10]-Substance P is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductance through nicotinic acetylcholine receptors[1].
Invitro Substance P (SP)-related peptide, pGlu-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2, inhibitS the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis[2].
Name [D-Trp7,9,10]-Substance P
CAS 89430-38-6
Sequence Arg-Pro-Lys-Pro-Gln-Gln-Trp-Phe-Trp-Trp-Met-NH2
Shortening RPKPQQWFWWM-NH2
Formula C79H105N21O13S
Molar Mass 1588.88
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.